Edge-to-edge mitral valve repair improves concomitant high-grade tricuspid regurgitation

Abstract Background Mitral regurgitation (MR) and tricuspid (TR) often occur simultaneously symptoms of biventricular heart failure can overlap. There is currently no consensus on the management combined MR TR. Purpose To evaluate impact TR echocardiographic functional outcome after M-TEER. Methods 740 patients underwent M-TEER for moderate-to-severe at our center from 2010 to 2021. Patients were analyzed according severity concomitant TR: low-grade (grade ≤ I (trace - mild)), moderate II) high-grade III V (severe torrential)). After M-TEER, followed up 12 months their was evaluated. Results Low-grade present in 279 (37.7%), 170 (23.0%) 291 (39.3%) time procedure. with had higher morbidity resulting EuroSCORE II STS-Score. At baseline more grade ≥III group (92.8% vs. 87.1% group; p=0.023). Procedural success achieved similarly all groups (98.2% 97.6% 95.9%, p=0.22). discharge 87.6% 80.9% residual ≤I (p=0.036). Residual 6.0% 10.5% (p=0.062). 3 increased 9.4% 13.4% (p=0.23) further 12.3% 15.3%, respectively (p=0.52). decreased rapidly consistently procedure only 48.0% still (p<0.001). this proportion declined 46.8% (p=0.99). High-grade significantly mortality (21.5% 18.2% 11.1%, p=0.003) However, TR-grade did not independently predict (HR 1.326, 95% CI 0.623–2.824, p=0.46). Conclusion compared patients. safe effective reduction independent severity. an risk but adverse outcome. group. Funding Acknowledgement Type funding sources: None.